An outpost of Louisville's popular art hotel, the 21c sits next door to the Contemporary Arts Center. The modern rooms have a Nespresso machine, free wi-fi, plush bedding and, of course, original art. The lobby is a public gallery, so feel free to ogle the trippy videos and nude sculptures. The on-site restaurant and rooftop bar draw crowds. Parking costs $38.
21c Museum Hotel Cincinnati
Top choice in Cincinnati