Innovatively created from the remains of the sprawling Santo Domingo monastery, this is Antigua's premier lodging. The 128 rooms and suites are of an international five-star standard, while the grounds retain their colonial splendor, dotted with archaeological relics and featuring a large swimming pool, several fine restaurants, five museums and lots of art. The Dominican friars never had it so good.
Free shuttles from the hotel take you to Santo Domingo del Cerro, a recently developed component of the complex atop a hill to the south, with a fine restaurant, an art and sculpture garden and stunning views.