Set back from the street in a gorgeous, plant-filled colonial courtyard, El Mural de los Poblanos serves excellent, traditional poblano dishes in an elegant setting. The house specialty is five kinds of mole. Other favorites include the smoky goat's-cheese-stuffed chile relleno and the trilogy of cemitas (burger unique to Puebla). Cocktails and other drinks are also excellent, and the service exceptional.
At different times of the year you can try local insect dishes such as escamoles (ant larvae).
Reservations are a good idea on busy Friday and Saturday nights and holidays; it's open 365 days a year.