Perugia's oldest hotel dates from 1786, but a complete 2017 makeover turned it into one of the city's sleekest digs. Stunning 18th-century frescoes juxtapose with glistening marble flooring, contemporary art and a minimalist grey-and-white colour scheme. None of the 17 rooms are the same, but modish elements like hardwood flooring and textured shower walls feature in several.
For a particularly memorable stay, try to snag room 108, a high-ceilinged suite with original frescoes.