Noble 19th-century palazzo turned 'luxury art hotel' is the essence of this boutique, five-star choice. Room decor features walls of art and shelves of books; amenities include Nespresso machines and Acqua Di Parma toiletries. The rooftop garden (with restaurant and cocktail bar) is one of Rome's best.
In the hotel's ground-floor, Michelin-starred restaurant Aquolino (menus €95 to €135), chef Alessandro Narducci cooks up sensational seafood dishes.