Cervejaria Blumenau's brewery in Itoupavazinha, 16km north of Centro, features 15 taps, the majority of which feature some of the city's best craft beer, including a great double IPA. This is the spot to go if you're not looking for strictly German-style brews, but the early closing time means you'll be day drinking!
An off-peak Uber runs R$25 or so.