For a dose of Bolivian history, it’s hard to beat this museum where the Bolivian declaration of independence was signed on August 6, 1825. It has been designated a national memorial and is considered the birthplace of the nation. Spanish-speaking guides are top flight – you'll likely applaud at the end of your guided tour.
The first score of Bolivian congresses were held in the Salón de la Independencia, originally a Jesuit chapel. Doctoral candidates were also examined here. Behind the pulpit hang portraits of Simón Bolívar, Hugo Ballivián and Antonio José de Sucre. Bolívar claimed that this portrait, by Peruvian artist José Gil de Castro, was the most lifelike representation ever done of him. The charter of independence takes pride of place, mounted on a granite plinth. A fine inlaid wooden ceiling and elaborate choir stalls are also noteworthy.
English- and French-speaking guides are available for groups of three or four minimum; you can, though, ask for free use of a tablet computer with text in English.