This museum is in a 1920s mansion in the neocolonial Peruvian style that developed as a reaction against French influences in turn-of-the-19th-century Argentine architecture. Its exceptional collection of colonial art includes silverwork from Alto Perú (present-day Bolivia), religious paintings and baroque instruments (including a Guarneri violin). The curved ceiling in the main salon is beautifully painted, and there’s also a peaceful garden. Signage is in Spanish.
Also known as the Palacio Noel, after the designing architect, the museum building and its collections suffered damage (since repaired) from the 1992 bombing of the Israeli embassy, which at the time was located at Arroyo and Suipacha. The space where the embassy was located has since become a small memorial park; you can still see the outline of the building on a neighboring wall.